Biomedical Lab Uses Shrinky Dinks Instead of $100K Diagnostic Chips

Michelle Khine's lab at UC Irvine couldn't afford the $100K equipment to make microfluidic chips, a sheet of material with tiny channels used for certain diagnostic tests, so she made her own with Shrinky Dinks. From the MIT Technology Review:

Racking her brain for a quick-and-dirty way to make microfluidic devices, Khine remembered her favorite childhood toy: Shrinky Dinks, large sheets of thin plastic that can be colored with paint or ink and then shrunk in a hot oven. "I thought if I could print out the [designs] at a certain resolution and then make them shrink, I could make channels the right size for micro­fluidics," she says.

To test her idea, she whipped up a channel design in AutoCAD, printed it out on Shrinky Dink material using a laser printer, and stuck the result in a toaster oven. As the plastic shrank, the ink particles on its surface clumped together, forming tiny ridges. That was exactly the effect Khine wanted. When she poured a flexible polymer known as PDMS onto the surface of the cooled Shrinky Dink, the ink ridges created tiny channels in the surface of the polymer as it hardened. She pulled the PDMS away from the Shrinky Dink mold, and voilà: a finished microfluidic device that cost less than a fast-food meal.

[via BoingBoing]


Comments

Newest comments listed first.

Posted by: GIGrafx on January 21, 2010 at 3:54 PM

Hacker Mentality

This is the way things should be... Being able to improvise with materials available. Great job!


Posted by: Pervy McPervyson on December 31, 2009 at 12:06 PM

they should make a movie about this and let her star in it.


Posted by: Michelle on December 21, 2009 at 6:24 PM

The headline is completely misleading. The article does not say the chips cost $100K it says the EQUIPMENT to make the chips is $100,000.


Posted by: the dude on December 18, 2009 at 2:06 AM

Glorious... now what?

Ok guys, It fantastic and she looks great. Can someone please comment on the actual fact: does this really work? I mean, if this works and microfluidic diagnostic chips can be made this way why doesn't it rock the nation a little instead of appearing on some blog?


Posted by: Anonymous on December 18, 2009 at 9:40 AM

who cares if it works? she can do whatever she wants


Posted by: Becky Stern on December 18, 2009 at 6:52 AM

You'll notice that the article I linked to is in the MIT Technology Review, a reputable source for news in early-stage technological discoveries.


Posted by: V on December 17, 2009 at 6:13 AM

Wow!

But then does this mean that microfluidic diagnostic chips are a huge scam?
If you can make one with shrinky dinks and some polymer goo, why on earth do they cost so much?


Posted by: Val on December 16, 2009 at 3:28 AM

Go Aardvarks!!


Posted by: Nikki on December 15, 2009 at 12:01 AM

Woaaaaaaaaaaaah

I go to UCI, and I'm surprised I didn't hear about this. This is amazing!


Posted by: Jason on December 15, 2009 at 8:52 AM

There are a lot of college and university students and faculty that knows on what has happened on campus. There have been a few changes on my campus, and signs up for months and articles in the (free) school newspaper and still a good portion of the students had no clue.


Posted by: Damon on December 13, 2009 at 6:40 PM

I want to marry this woman!!


Posted by: Dralf Pencilmore on December 12, 2009 at 2:57 PM

Shrinking dinks is an art, and she's the art teacher. Please excuse me if I say wrong, English is not my first language.


Posted by: Nick on December 12, 2009 at 2:16 AM

That's awesome, plus she's way hot.


Posted by: Mike W. on November 28, 2009 at 9:52 PM

Outstanding! Her ingenuity is incredible! This shows the power of creative thinking!


Posted by: mana on November 14, 2009 at 7:18 PM

amazing

this s amazing..
im imagining how the people who designed 100k$ equipment would have reacted to this..
they could not have hard time than this..


Posted by: Michael on November 11, 2009 at 9:30 PM

Fantastic!

I wonder how large of a contributing factor to the sky-high R&D costs in many industries is simply the availability of capital.


Posted by: non e mouse on November 10, 2009 at 11:06 PM

Genius

I always love a good story about someone finding an alternative to an overpriced item. Plus a practical use for Shrinky Dinks! lol


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